) in which the active component comprises A significant part of the pill and exactly where Charge of weight could be presumed to get an satisfactory Charge of drug articles uniformity. Weight variation isn't an suitable sign of content uniformity the place the drug compound comprises a relatively insignificant portion of the tablet, or where the pi

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In lots of conditions, baseline separation from the peaks might be obtained only with gradient elution and minimal column loadings. Consequently, two drawbacks to elution mode chromatography, In particular with the preparative scale, are operational complexity, due to gradient solvent pumping, and very low throughput, as a result of very low column